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KMID : 1007320170230020124
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Journal of the Korean Society of Menopause
2017 Volume.23 No. 2 p.124 ~ p.130
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The Effect of Short-term Treatment with Fennel on Bone Density in Postmenopausal Women: A Randomized Controlled Trial
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Ghazanfarpour Masumeh
Amini Elham
Khadivzadeh Talat
Babakhanian Masoudeh
Nouri Bahareh
Rakhshandeh Hassan
Afiat Maliheh
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Abstract
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Objectives: The goal of this study is to assess the effect of fennel on bone density.
Methods: This was a double-blind, randomized, placebo-controlled trial, which studied sixty eligible postmenopausal women, who were randomly assigned to fennel and placebo groups. Then, the dual energy X-ray absorptiometry was utilized to measure bone mineral density (BMD) and bone mineral content (BMC) of the spine, femoral neck, intertrochanter, and trochanter at the baseline and after three-month follow-up.
Results: The mean BMD and BMC at lumbar spine (P = 0.14, P = 0.504), total hip femoral (P = 0.427, P = 0.471), trochanter (P = 0.075, P = 0.07), intertrochanter, (P = 0.864, P = 0.932) and femoral neck (P = 0.439, P = 0.641) was not significantly different between the fennel and placebo groups.
Conclusions: The results of this study did not approve the effect of fennel on bone density in post-menopausal women. However, to gain deeper insights, further studies with longer durations and larger sample sizes are recommended. (J Menopausal Med 2017;23:124-130)
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KEYWORD
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Bone density , Foeniculum , Postmenopause
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